Most anti-aging supplements fail because they target a single pathway. But aging isn’t one problem—it’s a system-wide breakdown.

AEON was designed differently. Instead of focusing on just NAD or one ingredient, it combines NMN with a full-spectrum longevity stack to support cellular energy, reduce inflammation, and promote long-term repair—all in one daily protocol.

Our formula is bound to a Liposomal Delivery Matrix that increases the absorption of each compound by 200-300% (source). SO LESS IS MORE!

AEON is free of preservatives, additives, gluten, animal derived ingredients, and has 0 calories. It's rigorously tested by 3rd party labs for both potency, AND heavy metals to ensure you receive a premium product each, and every time (latest rest).

*This products formulation is kept up to date with the latest longevity research so the formula/ingredients may change slightly over time.

Nicotinamide DUO™ (NMN, NAD+) has been shown to have a variety of benefits including:

✅ 1. Increased Energy and Reduced Fatigue:

• NMN helps increase NAD+ levels, which are essential for mitochondrial energy production in cells. 

• This can lead to increased energy levels, reduced fatigue, and improved physical performance. 

   

✅ 2. Improved Muscle Function and Strength:

• NMN may help reverse age-related declines in muscle strength and size, which is called sarcopenia. 

• Studies have shown that NMN can improve muscle strength, endurance, and oxygen utilization in older adults and athletes. 

   

✅ 3. Enhanced Cognitive Function: 

• Some research suggests that NMN may improve cognitive function and protect against age-related cognitive decline, including in models of Alzheimer's disease.

• This could be due to NMN's ability to enhance energy metabolism in brain cells and reduce oxidative stress.

   

✅ 4. Protection Against Age-Related Decline: 

• NMN may help protect against various age-related declines, including those in the cardiovascular system, kidneys, liver, and other organs.

• It can also help maintain the integrity of the blood-brain barrier, which is important for brain health.

   

✅ 5. Other Potential Benefits:

• Improved Insulin Sensitivity:

   

  NMN may improve insulin sensitivity, which is important for maintaining blood sugar levels and preventing conditions like type 2 diabetes. 

   

• Reduced Age-Associated Weight Gain:

   

  NMN may help suppress age-related weight gain and improve body composition. 

Quercetin is a plant flavonoid found in many fruits, vegetables, and grains—especially onions, apples, and berries. It's widely used as a dietary supplement for its antioxidant, anti-inflammatory, and immune-supporting properties.

Here are the key potential benefits of taking quercetin:

✅ 1. Powerful Antioxidant

• What it does: Neutralizes free radicals and reduces oxidative damage to cells and tissues.

• Why it matters: Oxidative stress is linked to aging, cancer, and neurodegenerative diseases.

   

✅ 2. Anti-Inflammatory Effects

• Inhibits inflammatory enzymes and cytokines (like TNF-α, IL-6).

• May help reduce symptoms of chronic inflammatory conditions such as arthritis or allergies.

   

✅ 3. Supports Immune Function

• Enhances immune response while modulating excessive inflammation.

• Studied for use in viral infections (e.g., colds, flu, even COVID-19 adjunctive therapy) due to antiviral and immune-balancing effects.

   

✅ 4. Allergy Relief

• Acts as a natural antihistamine by stabilizing mast cells and reducing histamine release.

• May help alleviate hay fever (allergic rhinitis) and seasonal allergies.

   

✅ 5. Heart Health

• May reduce blood pressure, improve endothelial function, and lower LDL oxidation.

• Helps relax blood vessels through nitric oxide modulation.

   

✅ 6. Blood Sugar Control

• Improves insulin sensitivity and lowers blood glucose levels in some studies.

• May be helpful for people with metabolic syndrome or type 2 diabetes.

   

✅ 7. Brain Health & Neuroprotection

• May protect brain cells from oxidative damage and inflammation.

• Early evidence suggests benefits for memory and cognitive decline.

   

✅ 8. Exercise Recovery

• May reduce exercise-induced inflammation and oxidative stress, helping with muscle recovery and performance.

Resveratrol is a natural polyphenol found in red grapes, wine, berries, and peanuts. It has gained attention for its potential health benefits, especially related to aging and chronic diseases. 

Here's a summary of the main potential benefits of taking resveratrol:

✅ 1. Antioxidant Effects

• What it does: Neutralizes free radicals that damage cells.

• Why it matters: May reduce oxidative stress, a contributor to aging and disease.

   

✅ 2. Heart Health

• Improves endothelial function: Helps arteries stay flexible and improves blood flow.

• Reduces LDL cholesterol oxidation: May help prevent plaque buildup in arteries.

• Mild blood pressure-lowering effects.

   

✅ 3. Anti-Inflammatory Properties

• Resveratrol may reduce markers of inflammation such as CRP and TNF-α, potentially beneficial for conditions like arthritis or metabolic syndrome.

   

✅ 4. May Support Brain Health

• Neuroprotective effects: Animal studies suggest it may protect against cognitive decline by reducing oxidative stress and inflammation in the brain.

• May enhance cerebral blood flow and potentially benefit memory.

   

✅ 5. Potential Anti-Aging Effects

• Activates sirtuins (especially SIRT1), proteins associated with cellular health and longevity.

• Mimics some effects of caloric restriction, which is linked to lifespan extension in various organisms.

   

✅ 6. Blood Sugar Regulation

• May improve insulin sensitivity and help regulate blood glucose levels, especially in people with type 2 diabetes.

   

✅ 7. Anti-Cancer Potential

• Laboratory studies show it may inhibit cancer cell growth and promote apoptosis (cell death) in some cancers, though human evidence is still limited.

Fisetin is a naturally occurring flavonoid found in strawberries, apples, grapes, onions, and cucumbers. It's gaining attention for its unique role as a senolytic agent, meaning it helps clear out "senescent" cells—damaged cells that no longer divide and contribute to aging and disease.

Here are the main potential benefits of taking fisetin:

✅ 1. Senolytic Activity (Anti-Aging)

• Clears senescent cells, which accumulate with age and promote inflammation and tissue damage.

• May slow biological aging and improve tissue function in organs like the brain, liver, and kidneys (shown in animal studies).

• One of the most promising natural compounds for healthy longevity support.

   

✅ 2. Brain and Cognitive Health

• Crosses the blood-brain barrier and may protect against neurodegeneration.

• Shown to improve memory and reduce cognitive decline in animal models of Alzheimer’s.

• Reduces brain inflammation and oxidative stress.

   

✅ 3. Potent Antioxidant

• Neutralizes free radicals and enhances glutathione levels, the body’s master antioxidant.

• Helps protect cells and DNA from oxidative damage.

   

✅ 4. Anti-Inflammatory Effects

• Suppresses pro-inflammatory cytokines (like IL-6, TNF-α).

• May help manage chronic inflammatory conditions such as arthritis or metabolic syndrome.

   

✅ 5. Supports Metabolic and Cardiovascular Health

• Improves insulin sensitivity and may lower blood sugar.

• Potential to lower cholesterol and reduce arterial inflammation.

   

✅ 6. May Have Anti-Cancer Properties

• In lab studies, fisetin has shown the ability to inhibit tumor growth, induce cancer cell death, and prevent metastasis.

• Human studies are very limited but ongoing.

Astragalus (Astragalus membranaceus) is a traditional Chinese herb used for thousands of years, known primarily for its immune-boosting, anti-aging, and adaptogenic properties. Modern research supports many of its traditional uses, especially in the context of immunity, inflammation, and longevity.

Here are the key benefits of taking astragalus:

✅ 1. Immune System Support

• Stimulates white blood cell production, helping the body fight infections more effectively.

• Enhances both innate and adaptive immunity.

• May reduce the frequency and duration of colds and upper respiratory infections.

   

✅ 2. Anti-Aging & Longevity

• Contains compounds that support telomere maintenance, especially cycloastragenol and astragaloside IV.

• Telomeres protect DNA during cell division and their length is a biomarker of aging.

• Used in longevity stacks for its potential to slow biological aging.

   

✅ 3. Anti-Inflammatory Effects

• Reduces levels of inflammatory markers (like TNF-α, IL-6).

• Helpful for chronic inflammatory conditions like arthritis or inflammatory bowel disease.

   

✅ 4. Cardiovascular Health

• May help lower blood pressure, improve circulation, and protect the heart muscle.

• Shown to reduce oxidative stress and inflammation in blood vessels.

• Sometimes used alongside conventional treatments for heart failure.

   

✅ 5. Kidney Health

• Protects against diabetic nephropathy and other forms of chronic kidney disease in some studies.

• Reduces proteinuria and may improve overall kidney function (used widely in China as an adjunct therapy).

   

✅ 6. Adaptogenic & Anti-Stress Effects

• Helps the body adapt to physical and emotional stress.

• May improve resilience, reduce fatigue, and enhance energy levels without overstimulation.

   

✅ 7. Antioxidant Support

• Rich in flavonoids, saponins, and polysaccharides that neutralize free radicals.

• Protects cells and tissues from oxidative damage.

L-theanine is a unique amino acid found almost exclusively in green tea. It’s widely used as a supplement for its calming and nootropic (brain-enhancing) effects—without sedation or drowsiness.

Here are the main benefits of taking L-theanine:

✅ 1. Promotes Relaxation Without Drowsiness

• Increases alpha brain waves, associated with calm alertness and mental clarity.

• Often used to reduce stress and anxiety without making you sleepy.

• Helps “take the edge off” stimulants like caffeine.

   

✅ 2. Enhances Focus and Attention

• Improves concentration and task switching, especially when taken with caffeine.

• Common in nootropic stacks for productivity and studying.

   

✅ 3. Reduces Anxiety and Stress

• Modulates neurotransmitters like GABA, dopamine, and serotonin, helping regulate mood and anxiety.

• Shown in studies to reduce heart rate and cortisol during stressful situations.

   

✅ 4. Supports Better Sleep Quality

• Helps you fall asleep more easily and improves sleep depth and quality.

• Does not act like a sedative—more helpful for calming a busy mind before bed.

• Often combined with magnesium or melatonin in sleep formulas.

   

✅ 5. May Protect Brain Health

• Acts as a neuroprotective antioxidant, helping protect neurons from damage.

• May support long-term cognitive health and reduce risk of age-related decline (limited human evidence so far).

   

✅ 6. Helps with Mood and Emotional Balance

• Subtle mood-lifting effects, especially in people under stress or with mild anxiety.

• May help reduce symptoms of depression when used alongside other treatments.

EGCG (Epigallocatechin gallate) is the most abundant and active catechin in green tea, known for its strong antioxidant and anti-inflammatory properties. It's been widely studied for its effects on metabolism, heart health, brain function, and even cancer prevention.

Here are the key benefits of taking EGCG:

✅ 1. Powerful Antioxidant

• Neutralizes free radicals and protects cells from oxidative damage.

• Helps preserve DNA, lipids, and proteins from age-related deterioration.

   

✅ 2. Supports Weight Loss and Metabolism

• Boosts thermogenesis and fat oxidation.

• Often included in weight-loss supplements due to its mild metabolism-boosting effects.

• May help reduce visceral fat (the type linked to metabolic disorders).

   

✅ 3. Cardiovascular Health

• Lowers LDL cholesterol and triglycerides.

• Improves endothelial function (blood vessel health).

• Reduces blood pressure and arterial inflammation.

   

✅ 4. Brain Protection and Cognitive Support

• May protect against neurodegeneration by reducing inflammation and oxidative stress in the brain.

• Increases dopamine and acetylcholine levels, both important for mood and memory.

• Linked to lower risk of Alzheimer’s and Parkinson’s in some population studies.

   

✅ 5. Anti-Cancer Properties

• Inhibits the growth of various cancer cells in lab studies (e.g., breast, prostate, colon).

• Suppresses angiogenesis (formation of new blood vessels in tumors) and promotes apoptosis (cell death).

• Human studies are still inconclusive but promising.

   

✅ 6. Anti-Inflammatory Effects

• Suppresses key inflammatory pathways (NF-κB, COX-2).

• May help with chronic inflammation, including autoimmune conditions.

   

✅ 7. Blood Sugar and Insulin Regulation

• May improve insulin sensitivity and reduce fasting blood glucose levels.

• Potentially helpful for people with metabolic syndrome or type 2 diabetes.

TMG (Trimethylglycine), also known as betaine, is a compound naturally found in beets, spinach, and whole grains. It plays a key role in methylation, liver health, and cellular function, and it's often used in longevity and performance supplementation.

Here are the primary benefits of taking TMG:

✅ 1. Supports Methylation (Homocysteine Reduction)

• TMG donates methyl groups to convert homocysteine (a potentially harmful amino acid) into methionine.

• Why it matters: High homocysteine is linked to heart disease, stroke, cognitive decline, and poor methylation status.

• Often used alongside vitamin B12, B6, and folate to optimize methylation pathways.

   

✅ 2. Cardiovascular Protection

• By lowering homocysteine, TMG may reduce the risk of atherosclerosis, blood clots, and cardiovascular events.

• Supports the integrity and flexibility of blood vessels.

   

✅ 3. Liver Function Support

• TMG helps metabolize fats in the liver and prevent fatty liver disease.

• Often used in conditions like NAFLD (non-alcoholic fatty liver disease) to improve lipid metabolism.

   

✅ 4. Athletic Performance & Muscle Strength

• Supports creatine synthesis, which helps with muscle power and recovery.

• May improve hydration and endurance during workouts by acting as an osmolyte (helps cells retain water).

   

✅ 5. Cellular Hydration & Stress Protection

• As an osmoprotectant, TMG helps maintain cellular water balance and protects cells from stress-related damage.

• Especially valuable during dehydration, heat stress, or oxidative stress.

   

✅ 6. Cognitive and Mood Support

• Supports SAMe (S-adenosylmethionine) production, a key molecule in brain chemistry and mood regulation.

• May assist with mental clarity, focus, and emotional stability, especially in people with methylation imbalances.

Spermidine is a naturally occurring polyamine found in foods like wheat germ, soybeans, mushrooms, and aged cheese. It's rapidly gaining attention for its anti-aging and cellular renewal properties—especially due to its ability to promote autophagy, a key process in longevity science.

Here are the main benefits of taking spermidine:

✅ 1. Activates Autophagy (Cellular Cleanup)

• Autophagy is the process by which cells break down and recycle damaged components.

• Spermidine mimics the effects of caloric restriction or fasting, triggering autophagy without food deprivation.

• Helps maintain cellular health and function as you age.

   

✅ 2. Anti-Aging and Longevity

• Linked to increased lifespan in yeast, flies, mice, and potentially humans.

• May slow age-related decline by reducing cellular waste, inflammation, and mitochondrial dysfunction.

   

✅ 3. Supports Brain Health

• Promotes neuroprotection by reducing oxidative stress and enhancing autophagy in brain cells.

• Associated with better memory and cognitive performance, especially in aging adults.

   

✅ 4. Cardiovascular Protection

• May improve arterial elasticity, reduce blood pressure, and support heart cell health.

• Higher spermidine intake is linked to lower cardiovascular mortality in observational studies.

   

✅ 5. Enhances Mitochondrial Function

• Improves the quality control of mitochondria, which boosts cellular energy production and resilience to stress.

   

✅ 6. Supports Immune Function

• Maintains the youthfulness of immune cells (particularly T cells) by helping them remove damaged proteins and organelles.

   

✅ 7. Skin and Hair Health

• By promoting cellular renewal, spermidine may support healthier skin and hair, with some evidence suggesting benefits for hair growth cycles.

Piperine is the active compound in black pepper that gives it its pungent flavor—but more importantly, it's widely used in supplements for its ability to enhance nutrient absorption and provide anti-inflammatory and antioxidant effects.

Here are the main benefits of taking piperine:

✅ 1. Dramatically Enhances Nutrient Absorption

• Most well-known benefit.

• Increases the bioavailability of various nutrients and compounds, such as:

  • Curcumin (by up to 2000%)

  • Resveratrol

  • EGCG

  • CoQ10, selenium, B vitamins, and more

• Does this by slowing metabolism in the liver (inhibits CYP450 enzymes) and increasing intestinal absorption.

   

✅ 2. Anti-Inflammatory Effects

• Reduces production of inflammatory cytokines like IL-6 and TNF-α.

• May help with joint pain, chronic inflammation, and even neuroinflammation.

   

✅ 3. Antioxidant Support

• Neutralizes free radicals and reduces oxidative stress in tissues.

• May protect cells from DNA damage and lipid peroxidation.

   

✅ 4. Brain Health & Neuroprotection

• Shown in some studies to improve cognitive function and memory, particularly when combined with curcumin.

• May increase serotonin and dopamine levels in the brain, with potential mood benefits.

   

✅ 5. Metabolism and Weight Management

• May stimulate thermogenesis and fat metabolism.

• Often included in fat-burning supplements for its mild metabolic boost.